IVF failure
Couples undergoing IVF have very good chances of conceiving in the first attempt and every attempt. The success chance is much better than any other treatment for the same couple. However, there is always a possibility of failure.
IVF success depends on the patient factor as well as the clinic factor.
BFIтАЩs IVF labs are built to offer the best development conditions for embryos. All our IVF labs are class 1000 labs for the best culture environment. Latest generation fertilization equipment and culture incubators help in the best care of eggs, embryos and blastocysts. Know more about our infrastructure
BFI has years of experience in treating difficult cases means there is always hope! We always custom design highly individualized, personalized, and optimised ovarian stimulation, which can cause a big difference between results.Click here to know why Bavishi Fertility Institute is different.
To get 100% all-around protection for patients of IVF failure, our unique тАШSuraksha Kavach PackageтАЩ offers and includes all advanced techniques as a standard. Know more
BFI APPROACH TO FAILURE
BFI has a systematic approach to the investigation and treatment of failure. The most important thing is the meticulous analysis of the failed IVF cycle. Our team divides the cycle into small stages or fragments and investigates it thoroughly. We use our findings to fine-tune and improvise future treatment.
Stimulation
The number and quality of oocytes recovered in the treatment cycle are analysed. We decide the optimum dose and protocol of stimulation based on this. We may suggest long protocol, short protocol, Microdose flare protocol or minimum stimulation IVF in your case. If the number of oocytes is very less you may benefit from our signature ovarian rejuvenation or dual stimulation тАШDuoStimтАЩ.
Fertilization
Usually, 70% or more mature oocytes fertilise to create an embryo. When there is poor fertilization, sperm DNA fragmentation test and specialised genetic tests are advised in rare cases.
To achieve a better selection of sperm, we can use PICSI. This technique selects sperm that are able to naturally bind the eggтАЩs outer surface. This helps in choosing better quality sperm. Read more
For egg quality assessment and preventing egg damage during fertilization, we may use spindle view ICSI – polscope. This technique provides a very good tool to investigate egg quality and allows us to clearly identify the site for sperm injection in eggs. Read more
Embryo quality depends on fertilization also. Techniques to improve fertilization are also useful in case of poor quality embryos.
Embryo Selection
IVF failure can be caused by factors related to embryos in 70% and uterus and other factors in 30% of cases. Every good looking embryo is not capable of developing as a pregnancy and a healthy child. Evaluating and improving the quality and selecting the best embryo for transfer is crucial for IVF success.
Blastocyst Culture
The embryo of the 4th to 6th day after fertilization is called a blastocyst. Only 30 to 60% of embryos reach the blastocyst stage. The technique provides a natural selection of better embryos.
PGT (Preimplantation Genetic Testing)
Genetic abnormalities are very common at the embryo stage, even in excellent looking embryos or blastocysts. The genetically abnormal embryos fail to implant or cause miscarriage. PGT allows the selection of genetically normal embryos for transfer, thus maximising conception chance per transfer and reducing miscarriage risk. Read more
Uterine and pelvic factors
Hysteroscopy
The embryos need a good place to grow. The soil is as important as the seed. Hysteroscopy helps diagnose any problem in the uterine cavity and the endometrium, which can affect implantation. We can correct most of them at the same time. Even if hysteroscopy is apparently normal, a minor procedure for endometrium activation тАУ stimulation can be done to improve implantation. Read more
ERA Test
The Endometrial Receptivity Array ERA test studies the gene expression profile of the endometrium at the time of embryo transfer. It determines the best time for an embryo transfer to help us in fine-tuning the time of ET. Read more
Hydrosalpinx, Fibroids, Adenomyosis and adenomas, pelvic adhesion etc., may have to be evaluated and addressed appropriately if there is an expected benefit.
Maternal Factors
Thrombophilias
Thrombophilias are a group of blood clotting disorders that can cause miscarriage and may reduce the IVF success ratio. A blood test can check them. In case of a positive result, we may advise you of some medicines or injections.
Couple Genetic Study
Chromosome imbalances in husband or wife can greatly increase the chances of genetically abnormal embryos. These embryos fail to implant and can cause IVF failure. Chromosomes can be tested as a blood test. If a genetic abnormality is detected, PGT can help.
When IVF fails, whatтАЩs next?
Infertility Counselling
The safe environment provided by infertility counselling allows you to express your feelings and emotions. You don’t need to be concerned about offending your partner or anyone else in this situation. Instead of repressing your feelings and allowing them to worsen later, it can help you let them out. You can decide on coping mechanisms and techniques with the help of your counsellor throughout this process.
IVF Support groups
Connecting with these groups of people can help you feel a little less alone as you continue to pursue your dreams of having a family. It is a good idea to research IVF support groups within your local community. In addition to providing inspiration, hearing others’ stories can help you cope.
Endometrial Receptivity Assay (ERA)
An endometrial biopsy is carried out to determine if the uterus is receptive to implantation based on gene expression investigations. It assists the specialist choose the best day to implant the embryo.
Uterine Evaluation/Hysterosalpingogram (HSG)
The uterus and fallopian tubes will be examined during an in-depth uterine evaluation. For a successful IVF cycle, this knowledge helps to determine the exact tubal status, reducing failure risk by nearly 50%.
Additional IVF Cycles
A failed IVF cycle can lead to further attempts at IVF by individuals and couples. A successful IVF cycle requires multiple cycles.
Why choose Bavishi Fertility Institute for recovery after IVF failure?
- Experienced specialists: Bavishi Fertility Institute has a team of experts who specialize in handling complex cases, including recovery after failed IVF cycles.
- Personalized treatment plans: Each patient receives a tailored approach, with customized treatments designed to address the underlying causes of IVF failure and improve future success.
- Advanced diagnostic tools: BFI uses cutting-edge technology for detailed diagnostics, helping to identify issues that may have contributed to previous IVF failures.
- Comprehensive support: The institute offers emotional counseling, nutritional guidance, and lifestyle advice to support patients both physically and mentally through their recovery process.
- Innovative treatment options: BFI provides advanced techniques like ERA (Endometrial Receptivity Analysis) and Spindle View ICSI, designed to improve implantation and embryo quality for higher success rates in subsequent IVF cycles.
- Proven track record: Bavishi Fertility Institute has a strong history of helping patients recover from IVF failures and achieve successful pregnancies, making it a trusted choice for those looking to continue their fertility journey.
FAQs
IVF failure can be attributed to various factors including genetic abnormalities, uterine abnormalities, poor embryo quality, endometrial receptivity issues, lifestyle and health factors, and immunological issues.
BFI investigates failed IVF cycles by meticulously analyzing each stage of the cycle, from stimulation and fertilization to embryo quality and implantation. They use their findings to refine and optimize future treatments.
BFI employs techniques such as spindle view ICSI, PICSI, and Preimplantation Genetic Testing (PGT) to enhance egg and embryo quality and increase the chances of successful implantation.
The Suraksha Kavach Package offers comprehensive protection by including advanced techniques and treatments as standard. It is designed to address various factors that may contribute to IVF failure.
The timing of embryo transfer is crucial for implantation success. It is determined using tests like the Endometrial Receptivity Array (ERA), which analyzes the endometrial lining to find the optimal transfer time.
In cases of poor fertilization, BFI may use specialized techniques like PICSI to select better-quality sperm and spindle view ICSI to assess egg quality and improve fertilization outcomes.
Genetic testing, including comprehensive chromosomal testing and Preimplantation Genetic Testing (PGT), helps identify and select genetically normal embryos, reducing the risk of miscarriage and improving implantation rates.
Couples can consider starting another IVF cycle immediately or as soon as they are ready. Waiting too long might require additional tests and could potentially reduce egg count, while starting sooner may offer marginally better results.
Infertility counseling provides a safe space for expressing emotions and developing coping strategies. Support groups offer a sense of community, inspiration, and shared experiences, which can be valuable during the IVF journey.
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