
Dr. Himanshu Bavishi
MBBS, MD (Obstetrics & Gynaecology) · Infertility, IVF & Genetics
A high-magnification refinement of ICSI. By examining sperm in far greater detail, IMSI helps the embryologist select the most structurally normal sperm for fertilisation.

IMSI (Intracytoplasmic Morphologically Selected Sperm Injection) uses specialised lenses and software to magnify sperm far more than in conventional ICSI. This lets the embryologist examine the fine structure of each sperm and choose those that look most normal.
Selection happens in two stages — first at standard magnification, as in ICSI, and then under very high magnification to identify structurally normal sperm for fertilisation. Because the assessment is detailed and subjective, the experience of the embryologist is central to the technique.

Co-director & IVF Specialist · IVF & Andrology
Ahmedabad | Bavishi Fertility Institute
Last medically reviewed on . This page is educational and is not a substitute for personalised medical advice.
IMSI is generally recommended in specific situations rather than for all couples.
Where indicated, IMSI aims to improve sperm selection in difficult male-factor cases.
A high-magnification selection step is added to the standard ICSI workflow.
The semen sample is collected and prepared following the routine IVF-ICSI protocol.
Eggs are retrieved from the ovaries through a short, ultrasound-guided procedure.
Sperm are first selected at standard magnification, in larger numbers than finally needed.
Selected sperm are examined under very high magnification to identify those with normal fine morphology.
The chosen sperm are injected into the eggs, and the resulting embryos are cultured for several days before transfer.
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An in-house team of experienced embryologists performs every micro-manipulation with precision.
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Every fertility journey is unique. IMSI success rates depend on several medical and lifestyle factors.
Factors affecting success
IMSI does not guarantee pregnancy; success depends on the underlying causes of infertility and individual factors.
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IMSI is safe in experienced hands, but it has limitations.
IMSI assessment is detailed and subjective, so results depend heavily on embryologist experience.
IMSI costs more than conventional IVF / ICSI and is not available everywhere.
Sperm remain outside the body for longer during selection, which may, in theory, affect fertilising capacity.
IMSI is most relevant to specific male-factor cases.
Meet the Bavishi Fertility Institute specialists who treat patients with IMSI.
Yes — IMSI is considered safe when performed by experienced specialists, though, as with any procedure, potential risks should be discussed with your doctor.
IMSI is typically recommended for poor sperm morphology, recurrent IVF/ICSI failures, or previous poor embryo quality, rather than for every couple.
No. IMSI does not guarantee pregnancy; success depends on the underlying causes of infertility and several individual factors.
IMSI is a form of ICSI that uses much higher magnification to assess sperm structure in detail before injection, so the embryologist can select the most normal-looking sperm.
No specific adverse effects have been shown, although sperm being outside the body for longer during selection may, in theory, reduce fertilising capacity. This is minimised by careful lab conditions.
The procedure takes a few hours overall, covering sperm selection, egg retrieval and, subsequently, embryo transfer.
Maintain a healthy diet, avoid alcohol and tobacco, manage stress and follow prescribed medications. A short period of abstinence before giving the semen sample may improve morphology.
This page is for educational purposes and is medically reviewed by Dr. Parth Bavishi, MBBS, MD (Obstetrics & Gynaecology). It is not a substitute for personal medical advice — please consult our doctors for guidance specific to you.
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Helpful reads on IMSI from the Bavishi Fertility Institute specialists.
Everything you need to understand about IMSI — how it works, who it helps and what to expect on your journey.
A transparent look at IMSI costs, EMI options and the Suraksha Kavach package, so you can plan with confidence.
Practical, science-backed tools to help you understand your fertility — privately and instantly.
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