IUI process explained: What to expect at every step

Intrauterine Insemination (IUI) is often one of the initial and commonly recommended fertility treatments for individuals or couples trying to conceive. It is a simple, less invasive procedure that can significantly improve the chances of pregnancy in many cases. Having a clear understanding of how IUI works, what to expect during the process, and its potential benefits can help patients feel more confident, prepared, and supported as they take their first steps on the path to parenthood.

In this blog, we’ll walk you through the entire IUI procedure—step by step—so you know exactly what to expect at each stage.

What is IUI?

Intrauterine Insemination (IUI) is a fertility treatment in which specially prepared sperm is placed directly into the uterus around the time of ovulation. This increases the chances of fertilization by helping the sperm get closer to the egg.

Who can benefit from IUI?

IUI is commonly recommended for:

• Mild male infertility.
  
  
• Unexplained infertility.
  
  
• Cervical factor infertility.
  
  
• Ovulation issues.
  
  
• Couples using donor sperm.
  
  
• Same-sex female couples.

Step-by-Step guide to the IUI process

Step 1: Initial consultation and Fertility evaluation

Your IUI journey begins with a comprehensive consultation at the fertility clinic. This includes:

• Medical history review.
  
  
• Physical examination.
  
  
• Hormonal blood tests (AMH, FSH, LH, TSH, etc.)
  
  
• Ultrasound scan of the ovaries and uterus.
  
  
• Semen analysis for male partner.

Based on the results, our fertility specialists design a personalized treatment plan.

Step 2: Ovulation monitoring or Ovulation induction

Timing is critical in IUI. We either:

• Monitor your natural ovulation cycle using ultrasound and blood tests
  OR
  
  
• Stimulate ovulation using fertility medications (like Clomiphene Citrate or Gonadotropins) to produce one or more mature eggs.

Throughout this phase, we perform:

• Follicular scans to track egg development.
  
  
• Hormonal blood tests to monitor ovulation progress.

Step 3: Triggering ovulation

Once your follicle(s) reach the optimal size (usually 18–20 mm), a trigger injection (HCG) is given to induce ovulation. The IUI procedure is then scheduled approximately 36–40 hours after the injection.

Step 4: Sperm collection and Preparation

On the day of the procedure:

• The male partner provides a semen sample at a clinic.
  
  
• If using donor sperm, we thaw a pre-selected and screened donor sample.
  
  
• The sperm is then washed and concentrated to separate motile, healthy sperm and remove debris or chemicals that could irritate the uterus.

This process increases the chances of fertilization by improving sperm quality and volume.

Step 5: The IUI procedure

The IUI procedure is simple, quick, and usually painless:

1. You lie on the exam table, similar to a Pap smear.
   
   
2. A thin, flexible catheter is gently inserted through the cervix.
   
   
3. The prepared sperm sample is injected directly into your uterus.

The whole procedure takes just a few minutes. You may rest briefly afterward before returning to your normal routine.

Step 6: Post-IUI instructions & Medications

After the IUI:

• We may prescribe progesterone supplements to support the uterine lining.
  
  
• You’ll be advised to avoid heavy lifting or intense workouts for a few days.
  
  
• Most women resume normal activities within 24 hours.

Step 7: The two-week wait

This is the most emotionally challenging part for many couples. You’ll wait about 14 days before taking a pregnancy test. During this time:

• Avoid stress and maintain a healthy lifestyle.
  
  
• Continue taking medications as prescribed.
  
  
• Watch for early pregnancy symptoms (though not everyone will have them).

Step 8: Pregnancy testing & Next steps

After two weeks:

• A blood test (beta-hCG) is done at our clinic to confirm pregnancy.
  
  
• If positive, we schedule your first pregnancy scan after 10–14 days.
  
  
• If negative, we review your treatment and decide whether to repeat IUI or explore other options like IVF.

Success rate of IUI

At Bavishi Fertility Institute, our IUI success rates are among the highest due to:

• Expert fertility specialists.
  
  
• Advanced sperm preparation techniques.
  
  
• Tailored stimulation protocols.
  
  
• Continuous monitoring and care.

While success depends on factors like age, sperm quality, and underlying fertility issues, IUI can offer up to 15–20% success per cycle for the right candidates.

Why choose Bavishi Fertility Institute for IUI?

• Comprehensive Fertility Workup.
  
  
• World-class Labs and Equipment.
  
  
• Highly Experienced Team.
  
  
• Transparent Treatment Plans.
  
  
• Holistic Support & Counseling.

Conclusion

Intrauterine Insemination (IUI) is a minimally invasive, cost-effective, and hopeful first step on the journey to parenthood. It offers many couples a chance to conceive with less stress and fewer medical interventions compared to more advanced fertility treatments. With the right timing, guidance, and medical support, IUI can significantly improve the chances of achieving a successful pregnancy. Contact Bavishi Fertility Institute today to book your consultation and explore how IUI can bring you closer to your dream of having a baby.

Author bio

Dr Parth Bavishi

Dr Parth Bavishi, MD in Obstetrics and Gynecology, brings over 12 years of invaluable work experience to his role as Director of Bavishi Fertility Institute, leading a group of IVF clinics committed to helping couples realize their dreams of parenthood.

Bavishi Fertility Institute is dedicated to providing customized and personalized treatments which are simple, safe , smart and successful. Bavishi Fertility Institute works with success and satisfaction for all at heart. Providing an ideal blend of professional treatment and personalised care.

Dr Parth had special training in infertility at Bavishi fertility Institute, the Diamond Institute, USA, and the HART Institute, Japan.

Dr Bavishi is a distinguished expert in his field. In addition to his clinical practice, Dr Bavishi is the author of the acclaimed book, ‘Your Miracle in Making: A Couple’s Guide to Pregnancy,’ offering invaluable insights to couples navigating the complexities of fertility. He loves to empower patients to make the correct choice by education both online and offline.

His exceptional contributions have earned him the prestigious Rose of Paracelsus award from the European Medical Association. Dr Parth has been an invited faculty at many national and international conferences.

FAQs